Hypertension is usually present from childhood, but the condition can be detected later in life. Hypokalemia is a result of increased potassium secretion from the main cells and alkalosis a result of luminal electronegativity and increased exchange of H + to K + in the intercalated cells (Link to intercalated cells).
Treatment is salt restriction and amiloride, which is a drug that blocks ENaC. Spironolactone has no effect when increased sodium reabsorption is independent of aldosterone.