Contraception

Menstrual cycle

Types of contraceptives

Click on a contraceptive to see information about it.

Condom
Pearl index 18%
Use Forms a barrier to prevent sperm and egg from meeting/fertilizing
Side effects Latex allergy (Latex free available)
Contraindications None
Comments/benefits Protects against STD´s, including HIV
Pearl index: The number of failures of a contraceptive method per 100 women years of exposure = failure rate if 100 women use the method for 1 year (a number that allows comparison of the efficacy of contraceptive methods)
IUD – Copper (5 years usually)
Pearl index 0.8%
Use Insert into the uterus

Copper component affects sperm motility and survival and prevents the sperm from fertilizing the egg

Side effects Perforation of uterus/cervix: 1-2 in 1000
PID: less than 1%.
Expulsion: 5%
Irregular bleedings are common in the beginning
50 % chance of increased dysmenorrhea and menorrhagia
Contraindications Known or suspected pregnancy
PID
Cancer in cervix or corpus uteri
Undiagnosed abnormal uterine bleeding
Comments/benefits Normal menstrual cycle
Can be used as emergency contraception (inserted within 7 days after unprotected intercourse)

Before insertion:
Pregnancy test is recommended if pregnancy is not ruled out
Test for STD´s
Bimanual pelvic examination
Paracetamol 1 g and Ibuprofen 400mg one hour before the insertion

Pearl index: The number of failures of a contraceptive method per 100 women years of exposure (a number that allows comparison of the efficacy of contraceptive methods)
OTHERS
Sterilization
permanent contraception
Vasectomy (male)
  - Pearl index 0.15%

Tubal ligation/salpingectomy (female)
  - Pearl index 0.5%

Lactational amenorrhea method (LAM) Temporary contraception for new mothers; requires full breastfeeding day and night of an infant less than 6 months old
  - Pearl index 1-2%
  - prevents ovulation
Emergency contraception(ECP)
within 5 days of unprotected sex; should be taken as early as possible

ECP containing ullipristal acetate (Ellaone®)
  - Delays ovulation
  - Restart of COC needs to be delayed 5 days for efficiency, otherwise reduced effect of ECP

ECP containing levonorgestrel (Postinor®, Norlevo ®)
  - Delays ovulation

COC (“Yuzpe method”)
  - Delays ovulation

Copper bearing IUD (inserted within 7 days after unprotected intercourse)

Withdrawal (coitus interruptus) Ejaculation outside the vagina, keeping the semen away from the partner´s external genitalia
  - Pearl index 22%
Standard Days Method (SDM) Women track their fertile periods using cycle beads or other aids; avoiding unprotected sex during most fertile days
  - Pearl index 24%
Pearl index: The number of failures of a contraceptive method per 100 women years of exposure (a number that allows comparison of the efficacy of contraceptive methods)
Combined oral contraceptives (COC) = estrogen + progestin Sold in Norway e.g.: Microgynon®, Loette®, Synfase®, Mercilon®, Zoely®, Qlaira®, Yasmin®, Yasminelle®
Pearl index 9%
Use Must remember to take the pill every day

Prevents the release of eggs from the ovaries
Thinning the endometrium
Thickening the cervical mucus

Side effects Mild: Headache, nausea, mood changes/depression, spotting, bloating, breast tenderness, decreased sex drive

Severe: Venous- or arterial thrombosis
Cancer (breast-, cervix cancer)
Differing hormonal levels (high and low dosed) with differing thrombosis risk (e.g. depending on gestagen doses)

Contraindications Previous venous- or arterial thrombosis
Current breast cancer
Migraine with aura
Diabetes with nephron- or neuropathy
Hypertension
Liver cirrhosis
Antiphospholipid antibody syndrome (APS)

Reduced effect of COC if medication for epilepsy

Comments/benefits Reduces menorrhagia and PMS (Premenstrual Syndrom)
Reduces dysmenorrhea (treating endometriosis and adenomyosis)
Reduces acne and hirsuitism if PCOS
Decreased risk of endometrial, ovarian and colon cancer
Long menstrual cycles is an option
Pearl index: The number of failures of a contraceptive method per 100 women years of exposure (a number that allows comparison of the efficacy of contraceptive methods)
Progestin-only pill (POP) Sold in Norway e.g.: Cerazette®, Desogestrel®
Pearl index 9%
Use Must remember to take the pill every day, POP is taken continuously without a break

Suppressing ovulation
Thinning the endometrium
Thickening the cervical mucus

Side effects Mild: Bloating, nausea, breast tenderness, spotting, irregular bleedings, amenorrhoea, acne, mood changes/depression

Severe: none

Contraindications Breast cancer
Comments/benefits Can be used while breastfeeding
Can reduce migraine
Reduces dysmenorrhea
Many women experience amenorrhea, others may have irregular bleeding.
Pearl index: The number of failures of a contraceptive method per 100 women years of exposure (a number that allows comparison of the efficacy of contraceptive methods)
Vaginal ring (COC vaginal insert) Sold in Norway e.g.: Nuvaring®
Pearl index 9%
Use The ring can stay in the vagina during intercourse
Needs to be changed every 3 weeks

Prevents ovulation (release of eggs from the ovaries)
Thinning the endometrium
Thickening the cervical mucus

Side effects Headache, nausea, mood changes, disturbances in menstrual bleeding patterns, pimples, decreased sex drive
Contraindications Previous venous- or arterial thrombosis
Current breast cancer
Migraine with aura
Diabetes with nephro- or neuropathy
Hypertension
Liver cirrhosis
Antiphospholipid antibody syndrome (APS)
Comments/benefits Often less side effect than COC
Reduces dysmenorrhea
Thrush or bacterial vaginosis can be harder to treat
Long menstrual cycles is an option
Pearl index: The number of failures of a contraceptive method per 100 women years of exposure (a number that allows comparison of the efficacy of contraceptive methods)
IUD- Levonorgestrel Sold in Norway e.g.: Mirena® (5 yrs), Levosert® (5 yrs), Kyleena® (5 yrs), Jaydess® (3 yrs)
Pearl index 0.2%
Use Inserted into the uterus

Releases small amounts of Levonorgestrel each day
Thickens cervical mucous to block sperm and egg from meeting/fertilizing

Side effects Perforation: 1-2 in 1000
PID: less than 1%. Removal is not routinely required.
Expulsion: 5%
Irregular bleedings are common in the beginning
Heavier bleedings for some users
Differing progestin levels (high and low dosed) with differing risk of side effects (e.g. depending on gestagen doses)
Contraindications Known or suspected pregnancy
Known or suspected breast cancer
PID
Cancer in cervix or corpus uteri
Undiagnosed abnormal uterine bleeding
Liver tumours, severe cirrhosis, or acute liver disease
Comments/benefits Women who cannot use estrogen
Changed bleeding pattern at 1 year of use:
  50% amenorrhea
  25% oligomenorrhea
  11% spotting

Mirena:
Reduces dysmenorrhea (treating endometriosis and adenomyosis)
Treatment of endometrial hyperplasia and cancer
Endometrial protection when using estrogen or Tamoxifen

Mirena and Levosert:
Treatment for heavy menstrual bleedings

Jaydess:
Recommended for nullipara

Before insertion:
Pregnancy test if pregnancy is not ruled out
Test for STD´s
Bimanual pelvic examination
Paracetamol 1 g and Ibuprofen 400 mg one hour before the insertion

Pearl index: The number of failures of a contraceptive method per 100 women years of exposure (a number that allows comparison of the efficacy of contraceptive methods)
Birth control patch (COC patch) Sold in Norway e.g.: Evra®
Pearl index 9%
Use Important to replace the patch every week

Prevents ovulation (release of eggs from the ovaries)
Thinning the endometrium
Thickening the cervical mucus

Side effects Breast tenderness, headache, nausea, mood changes,
disturbances in bleeding patterns, pimples, decreased sex drive
Contraindications Previous venous- or arterial thrombosis
Current breast cancer
Migraine with aura
Diabetes with nephro- or neuropathy
Hypertension
Liver cirrhosis
Antiphospholipid antibody syndrome (APS)
Comments/benefits Reduces dysmenorrhea
Long menstrual cycles is an option
Pearl index: The number of failures of a contraceptive method per 100 women years of exposure (a number that allows comparison of the efficacy of contraceptive methods)
Progestin-only injectable Sold in Norway e.g.: Depo-Provera®
Pearl index 6%
Use Injected intramuscularly or subcutaneously every third month

Suppressing ovulation
Thinning the endometrium
Thickening the cervical mucus

Side effects Weight gain, irregular vaginal bleedings, osteoporosis, headache, acne, breast tenderness
Contraindications Breast feeding (first 6 weeks)
Ischemic heart disease or stroke
Hypertension
Multiple risk factors for fractures and osteoporosis
Multiple risk factors for heart disease
Severe celiac disease (osteoporosis)
Diabetes with nephro- or neuropathy
Breast cancer
Comments/benefits Reduces menorrhagia
Reduces dysmenorrhea (treating endometriosis)
Many people lose their bleedings completely (50% after the first year)

Delayed return to fertility

Pearl index: The number of failures of a contraceptive method per 100 women years of exposure (a number that allows comparison of the efficacy of contraceptive methods)
Implant (progestin- only), 3 years Sold in Norway e.g.: Nexplanon®
Pearl index 0.05%
Use Placed under the skin of the upper arm

Primarily prevents ovulation
Thickens cervical mucous to block sperm and egg from meeting

Side effects Delayed fertility (about 1–4 months on average) after use
Changed bleeding pattern:
  1/3: regular bleedings
  1/3: Irregular bleedings
  1/3: no bleedings
Method specific side effects: Nerve or vascular injury, deep insertion, non insertion
Contraindications Undiagnosed abnormal uterine bleeding
Liver tumours, severe cirrhosis, or acute liver disease
Comments/benefits Highest efficiency
Pearl index: The number of failures of a contraceptive method per 100 women years of exposure (a number that allows comparison of the efficacy of contraceptive methods)

Special care groups

Special care group
Postpartum & Breastfeeding

Progestin-only pill (POP) and implant.

After 6 weeks: Can also choose progestin injection

After 6 months: Can also choose combined oral contraceptive (COC), patch and vaginal ring

Directly postpartum IUD insertion (chosen in several low-income countries with poor access to postpartum health care)

Estrogen may suppress lactation

Estrogen increases risk for venous thrombosis

Postpartum & Not breastfeeding

All progestin contraception

After 6 weeks: COC, patch and vaginal ring

Be aware of increased risk of venous thrombosis (especially the first 5-6 weeks postpartum)

Epilepsy (women who are on antiepileptic drugs) IUD, progestin injection or implant

Some antiepileptic drugs (AEDs) may make COC less effective

Estrogen may make some AEDs less effective

After abortion

Surgical: All contraception methods can be started the same day

Medical: All methods
IUD after one week

Breast cancer Non hormonal Hormonal receptor- negative breast cancer & cancer- free after treatment: Can use any method (consult oncologist)
Diabetes mellitus (DM) All progestin methods (Progestins may effect insulin resistance, therefore cautious blood sugar control the first months of use with medroxyprogesteronacetat (Cerazette))

Non–vascular DM:
can also use COC, patch and vaginal ring

DM with vascular complication, DM for more than 20 years or DM with risk for arterial vascular disease:
COC, patch and vaginal ring not recommended

Estrogen increases risk for thrombosis
Women with increased risk of venous or arterial thrombosis
(Previous thrombosis, inherited disorder for thrombosis, hypertension, smoking, hypercholesterolemia, DM, BMI > 30)
All progestin Estrogen increases risk for thrombosis
Dysmenorrhea
Endometrioses (and adenomyosis)
IUD – Mirena
Progestin injection
POP
Progestin implant
COC - recommend that the pill is taken daily continuously for effect on pain (achieve amenorrhea)
Achieve amenorrhea
Menorrhagia IUD- Mirena, Levosert
COC
Migraine

All progestins.

The POP/COC may reduce migraine- related attacks

Migraine with aura:
Estrogen increases risk of stroke

Migraine with no aura and < 35 yrs:
can use contraception with estrogen

Estrogen is associated with a very small increased risk of ischemic stroke

The initial contraception consultation

IUD/Nexplanon insertion

Extended regimen COC

How does it work?Extended regimen or continuous cycle COC reduces or eliminates the withdrawal bleeding that would occur every 28 days. It works by reducing the frequency of the pill- free or placebo days. It is an effective and safe option.
Patient groups

For women who suffer from hormone withdrawal symptoms and cyclical symptoms (e.g. headache, mood changes, dysmenorrhoea, heavy menstrual bleeding)

For women who want to reduce the interference of scheduled bleeding with daily activities, such as sexual activity, exercise, sports and work.

EfficacyThe contraceptive efficacy of extended regimen COC is comparable to that of conventional 28-day (i.e., 21/7) regimens.

What if you forget a pill?

POP Cerazette®Should be taken within 12 hours if forgotten (within 36 hours after the last pill)
POP Conludag® mini pillShould be taken within 3 hours if forgotten (within 25 hours after the last pill)
COCShould be taken within 24 hours if forgotten (within 48 hours after the last pill)
Emergency contraception (ECP)

Within 5 days of unprotected sex; should be taken as early as possible

ECP containing ullipristal acetate (Ellaone®)

  • Delays ovulation
  • Restart of COC needs to be delayed 5 days for efficiency, otherwise reduced effect of ECP

ECP containing levonorgestrel (Postinor®, Norlevo ®)

  • Delays ovulation

COC (“Yuzpe method”)

  • Delays ovulation

Copper bearing IUD

  • Inserted within 7 days after unprotected intercourse