Ovary with Brenner tumor
Clinical story
58 years old woman who previously underwent hysterectomy. A cystic tumor of the right ovary was detected by CT. Bilateral salpingo-oophorectomy was performed.
Comments
Gross appearance: the right ovary consisted of a large (20x10x10 cm) multilocular serous lesion, grossly diagnosed as a cystadenoma. An enlarged left ovary (7x4x4 cm) with a yellow to white cut was also found. A section from the left ovary was taken for histopathological examination.
Microscopy: groups and strands of epithelial cells in an abundant, fibrous stroma. Some of the epithelial cell nests have lumina with eosinophilic material or mucin. The majority of epithelial cells are polygonal and pale with oval nuclei, some of which have a central longitudinal groove. Areas with calcification (blue areas) are found.
Learning goals
To recognize Brenner tumor, its association with mucinous tumors and its unclear histogenesis.