Ovary with immature teratoma
Clinical story
25 years old female with a large (16 cm) tumor in the left ovary. Low volume ascites. No metastases.
Comments
Grossly, heterogeneous cut section, partly cystic and partly solid. Section from
the ovarian tumor.
Microscopy: Mature components from all 3 germ layers are seen in the tumor. Additionally, large areas with immature neuroectodermal differentiation are found, some with tubule formation, some solid and recognized as blastemal pattern. The area with immature elements was large, qualifying for grade 3
tumor.
Learning goals
To recognize immature teratoma as a germ cell tumor; To identify its different components; To understand the clinical significance of malignant transformation in terms of metastasis, treatment and prognosis.