Ovary with mucinous cystadenoma with atypia (mucinous borderline tumor)

Clinical story

62 years old female with a large cystic tumor in the left ovary. Hysterectomy,

bilateral salpingo-oophorectomy, omentectomy and appendectomy. The enlarged ovary weighed 984 g, with a largest diameter of 17 cm.The surface was smooth. The cut section showed partly cystic, partly solid tumor with mucous.

Virtual microscopy of the slide

Comments

Microscopy reveals multiple cystic spaces of variable diameter. The cysts are lined by columnar epithelium with mucin in the cytoplasm. The degree of atypia is variable, with some areas containing atypical cells with overlapping nuclei.

Learning goals

To recognize borderline mucinous tumor of the ovary. Additionally, to understand the division of epithelial tumors of the ovary by histological type and the degree of malignancy, as well as the potential of borderline tumors to become adenocarcinomas.