Neuroblastoma in adrenal gland
Clinical story
A 1 year old boy with failure to thrive. By ultrasound, a circumscribed tumor was discovered in the adrenal gland. No metastases were found after X-ray of the lungs and abdominal MR. The tumor was resected without prior chemotherapy and measured 2.5 cm in diameter.
Comments
The cortex of the adrenal gland is intact around the tumor, which is situated in the medulla. The tumor nuclei are slightly pleomorphic, lying in an eosinophilic matrix of neuropil, and with a lobular appearance due to small vessels. The typical organization of nuclei in rosettes is seen. Mature ganglion cells are not found.
Learning goals
Recognize the tumor, its typical location, origin and diagnostics.