Molar pregnancy, complete hydatiform mole

Clinical story

38 years old female, 14 weeks pregnant. Ultrasound showed and "empty ovum" and changes suspicious of hydatiform mole, and a uterine evacuation of abundant material was performed. At gross inspection, multiple small cysts were

recognized.

Virtual microscopy of the slide

Comments

Blood clots and enlarged, irregular and avascular placental villi with considerable hydropic appearance are seen. The trophoblast layer is focally thickened and with numerous syncytiotrophoblasts, randomly distributed along the villous surface. No normal villi with polarized trophoblastic growth and vessels are found.

Learning goals

To recognize pathological villi of early pregnancy and have knowledge about the etiology and epidemiology.