Instruksjon til oppgaven Zinc finger proteins are the most common class of transcription factors. Typically, the Zn finger is a sequence of about 30 amino acids including 2 cysteines in a beta-sheet hairpin structure, 2 histidines on an-alpha helix, and 3 hydrophobic residues, all at conserved positions. The interaction of Cys and His sidechains with Zn holds the beta-hairpin and alpha-helix tightly together. The alpha-helix binds in the major groove of the DNA molecule. Choose from one to all of the alternativesEach Zn finger recognises a 3 base-pair sequence on the DNA.A Zn finger protein contains a single Zn finger which gives it a unique sequence specificity.Metallothioneins are transcription factors containing a Zn finger, that regulate genes involved in binding and storing surplus metal ions. Zn is not stored in the body, so a serious reduction in Zn intake is followed very quickly by signs of deficiency.Phytate – a phosphorylated hexose sugar found in wholegrain foods – binds Zn and assists its uptake through the intestinal wall.Send svaretReset quiz
